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Hakim Sabzevari University
Roya Askari, PhD
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Halima Vahdatpour
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Showing 2 results for Siahkouhian

Behrouz Heidari, Marefat Siahkouhian, Ali Zarghami,
Volume 7, Issue 13 (Volume 13, Number 1, 2014-2015 2015)

Introduction: Silybum marianum is an annual or biannual herbaceous species of the Asteraceae family. The medicinal effects of this plant are due to the presence of a group of flavonolignans which is called silymarin. It has been suggested that silymarin has anti -inflammatory, antioxidant properties and could stabilize cell membranes and regulate cell permeability and could prevent the appearnance of some of the undesirable muscle damage indices in patients and even athletes. Hence, the aim of this study was to determine the effect of silymarin intake on some mascular damage markers in serum of active males after the one session aerobic exercise.

Methods: Twenty-two active males (mean age 25.09±2.11 years, body fat 13.56±1.94% and VO2max 50.5±4.88 ml/kg-1/min) were divided into two homogenous groups of 11 subjects (supplement and placebo groups) in a semi-experimental, randomized and double-blind design (6 mg.kg-1.day silymarin or Dextrose). After 7-days of supplementation, all subjects participated in aerobic exercise protocol including running on the treadmill at the 0% grade for 30 min with 65-70% HRreserve. Changes in muscle damage indices (total serum CK and LDH, AST) were determined in four phases (baseline, after supplementation period, immediately and 24 hours after the exercise). Data were analyzed by repeated measure ANOVA, bonferroni, and independent t test at α≤0.05 level of significance.

Results: The results showed that after 30 min aerobic exercise, the levels of serum muscle damage enzymes significantly increased immediately and 24 hours after exercise in Silymarin and Placebo groups (P≤0.05). However, after 24 hours of aerobic exercise, all of muscle enzymes activity was signficiantly higher in Placebo group in comparison with Silymarin group (P≤0.05).

Conclusions: Based on the present findings, it could be concluded that silymarin supplementation could significantly decrease further aerobic exercise-induced muscle damage in active males.

Marefat Siahkouhian, Leila Fasihi, Aidin Valizadeh, Abbas Naghizadeh, Lotfali Bolboli,
Volume 19, Issue 19 (Volume 19, Number 1, 2018 2018)

Introduction: Quantifying the relationship between volume and intensity as key components of training is a precise manner that is complicated for most coaches. The aim of this study was to quantify the inverse relationships between training volume and intensity during exhaustive treadmill running among active young men.
Methods: 32 active young men aged 21 years selected as subjects and completed four exhaustive treadmill running in the four separate phases at 70%, 80%, 90%, and 100% VO2 with at least 72 hours rest intervals. The inverse relationship between regression.
Results: The results showed that the inverse relationship between volume and intensity of exhaustive treadmill running obeys a second-order polynomial regression where the volume of exercise (VE min) is a function of exercise intensity (EI beat/min) (VE min= 0.0225(HR beat/min) 2 – 9.4672 (HR beat/min) +997.91).
Conclusion: It can be concluded that the inverse relationship between volume and intensity of exhaustive treadmill running is non-linear and the fitted equation can be used to predict the volume of exercise based on the exercise intensity among active young men.

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