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:: Volume 8, Issue 16 (Volume 16, Number 2, 2016-2017 2016) ::
3 2016, 8(16): 54-61 Back to browse issues page
Effects of eight weeks of resistance training on serum SFRP5 concentration in obese men
Abstract:   (726 Views)

Introduction: Secreted frizzled-related protein 5 (SFRP5), like adiponectin, is considered as a novel adipokine with insulin-sensitizing and anti-inflammatory characteristics. The purpose of this study was to investigate the effect of eight weeks of resistance training on serum SFRP5 concentration in obese men.

Methods: Twenty four obese men (age; 36.9 ± 8.5 yr, weight; 94.8 ± 10.7 kg, and BMI; 31.7 ± 2.4) voluntarily participated in this study and were divided into control and resistance training groups (n=12). Subjects in training group performed eight weeks resistance training in a circuit manner with 50-85% 1RM (3 days/week). Anthropometrics parameters and fasting serum glucose, insulin, and SFRP5 concentrations, as well as insulin resistance index (HOMA-IR) were measured at the baseline and at the end of study.

Results: Resistance training induced significant reductions in body weight, BMI, body fat percentage, waist and hip circumferences (P< 0.05). Also, significant reductions in serum insulin concentration and HOMA-IR scores were found when compared with control group (P<0.05). Eight weeks of resistance training did not significantly change in serum SFRP5 concentration in training group. Nevertheless, a significant decrease was found in the control group (P<0.05). The result of analysis of covariance (ANCOVA) showed a significant difference between the two groups in changes in serum SFRP5 concentrations (P<0.05).

Conclusion: It seems that resistance training could improve metabolic conditions at least by preventing a decrease in serum SFRP5 levels.

Keywords: Obesity, SFRP5, Insulin resistance, Resistance training.
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Received: 2017/11/7 | Accepted: 2017/11/7 | Published: 2017/11/7
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Effects of eight weeks of resistance training on serum SFRP5 concentration in obese men. 3. 2016; 8 (16) :54-61
URL: http://journals.hsu.ac.ir/sbs/article-1-706-en.html


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