Introduction: Some previous studies have indicated that short-term caffeine supplementation can improve exercise performance and fat oxidation. The purpose of this research was to examine the effect of one dose caffeine consumption on lipolysis following maximal endurance exercise in physically active women.

Materials and Methods: In a counter-balanced design research 9 trained women (age: 22.3±2.8 years; weight: 61.7±8.1kg, height: 167.7±6.7 cm; BMI: 22± 2.2 kg/m) participated voluntarily in 3 sessions who consumed randomly caffeine (6 mg/kg/day), Caffeine-carbohydrate (6 mg/kg/day Caf+3 mg/kg/day CHO) and placebo (250 mg maltose). They received supplement or placebo in form of capsule 1 hour before Bruce test. Between each session one week was supposed for wash out. Blood samples were collected 3 times in each session: At first, at 8 am (in fasting condition), second, 1 hour after receive supplement and immediately after finishing Bruce test, and third, 1 hour after Bruce test.

Results: Analysis variance with repeated measure shows that there were no statistically changes in lipid profile variables (TG, Chol, HDL, LDL), free fatty acids, cortisol and hormone sensitive lipase by receiving one dose of caffeine or caffeine-carbohydrate supplements and some of changes was affected by doing maximal endurance exercise not by supplement consumption.

Conclusion: Altogether, current study shows that consuming one dose of caffeine or caffeine-carbohydrate did not effect on lipid metabolism and aerobic function.